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Key Takeaways Starting TRT dosage is typically 100-125mg weekly, split into two injections Target testosterone levels should fall between 450-600 ng/dL for optimal results Injection frequency of every 3.5 days provides more stable hormone levels than weekly dosing Regular monitoring every 3-6 months prevents adverse effects and ensures proper optimization Individual response varies significantly, requiring personalized dose adjustments over 3-6 months Standard TRT Starting Protocols Most endocrinologists begin testosterone replacement therapy with 100-125mg of testosterone cypionate or enanthate per week
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