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Remove the nasal spray from the packaging and lay the person on their back Hold the nasal spray with your thumb on the bottom of the plunger and your middle fingers on either side of the nozzle Tilt the person’s head back and insert the nozzle into one nostril until your fingers are against their nose Press the plunger firmly to give the dose and then remove from the person’s nose If the person does not respond in 2-3 minutes, give a second dose from a new nasal spray (if available) Instructional Videos If you or someone you know is at risk for opioid overdose, it is important to have naloxone available

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BPC157 also modulates immune system function, gene expression, and hormone regulation in gastrointestinal nervous system as well as the coagulation cascade